Genetic Disorder Statistics in India

The occurrence of genetic disorders in India is increasing at an alarming rate. Genes play a crucial role in transmitting various genetic disorders from one generation to the other. Certain diseases are passed from parents to children. Some genetic disorders are community specific because of certain mutations in the same gene pool.
One or more abnormal changes in DNA can cause a genetic disorder. Control and management of genetic disorder depend on the identification of genetic variants in the genome causally linked with the disease. There are hundreds of different genetic disorders reported in India. Some of the most common genetic disorders observed in India are:

  • Down Syndrome
  • Thalassemia
  • Cystic Fibrosis
  • Sickle Cell Anemia
  • Tay-Sachs disease
  • Spinal Muscular Atrophy
  • Hemophilia A
Epidemiology of Genetic  Disorders in India

A load of genetic disorders is high in certain communities due to the practice of consanguineous marriages in those communities. In cities, congenital malformations and genetic disorders are the main reason behind morbidity and mortality.

Some genetic disorder statistics in India are listed below:
  • The carriers of genetic disorders live a healthy life and may never show any symptoms throughout life. However, if both parents are carriers of mutated gene the risk of the infant being affected is as high as 25%.
  • According to the Union Ministry of Health and Family Welfare, over eight crore people suffer from genetic conditions.
  • A study reported the birth defect pervasiveness in India as 64.4 per 1000 live births.
  • The most common birth defect observed is musculo-skeletal disorders and neural tube defects.
  • A study reports that non-consanguineous couples were prone to transmission to their offspring by almost 6%.
  • Statistics show that 1 in every 25 individuals suffer from cystic fibrosis but shows no symptoms.
  • The frequency of Down syndrome was 0.87 per 1000.
  • Beta-thalassemia has shown a frequency of 1:2700 at birth, which means that approximately 9,000 cases of thalassemia major are born each year.
  • Sickle cell anemia affects 1 in every 150 live births. Almost 5200 infants are born with this disorder every year.
  • Spinal muscular atrophy affects approximately 1 in 10,000 newborns, and about 1 in every 50 live births is a genetic carrier for the disease.
  • There are about 17,000 hemophiliacs in India.
The figures state that it is high time we should consider genetic screening for early detection and preventive strategy planning.  It is not possible to cure genetic conditions but it is crucial to identify the predisposition to diseases and reduce the risk of mortality. Genetic testing helps us plan our health checkups and screening for any familial genetic condition

Let's Talk About PCOS: Signs, Symptoms And Treatment

What is Polycystic Ovary Syndrome (PCOS)?
Polycystic ovary syndrome (PCOS) is a hormonal disorder affecting women of reproductive age. PCOS affects your child-bearing ability, irregular menstrual cycle and production of excess male hormone (androgen). This syndrome increases health risks to develop diabetes and high blood pressure. Excessive androgen may stimulate hair growth and acne.

Signs And Symptoms Of PCOS
A few women observe PCOS symptoms around the time they have their first period. Only a few of them discover these signs of polycystic ovary syndrome (PCOS) when they face trough getting pregnant or they’ve gained too much weight. 

Common PCOS symptoms are:
  • Heavy bleeding and irregular periods
  • Hirsutism or excessive hair growth
  • Acne breakouts
  • Male-pattern baldness
  • Weight gain
  • Darkening of the skin
  • Severe headaches

PCOS Causes
The exact risk factors or causes of PCOS are not known. The factors that might play a major role are as stated below:
  • Heredity or genetic factors:
  • Excessive insulin: Increase in the production of insulin in the cells causes an increase in androgen (male hormone) production. This phenomenon interferes with ovulation.
  • Excess androgen production: Resulting in acne and hirsutism.
  • Low-grade inflammation: Low-grade inflammation of cells stimulates the polycystic ovaries to generate more androgens. This problem can lead to heart and blood vessel health risks.
The diagnosis of PCOS is done in three steps as mentioned below:
  • pelvic exam by the physician
  • Blood tests to measure hormone levels in the body
  • An ultrasound to check the appearance of your ovaries and the thickness of the lining of your uterus

If your doctor diagnosis PCOS he might recommend additional tests for complications.

Polycystic Ovary Disease (PCOS) Treatments
Treatment includes:
Birth control pills: Estrogen and progestin regulate hormone balance and ovulation.
Metformin: Treats PCOS by regulating insulin levels.
Clomiphene: This is a fertility drug that improves the chances of pregnancy. However, it also increases the risk of multiple births.
Hair removal medicines: Eflornithine cream, laser hair removal, and electrolysis can use used
Surgery: Ovarian drilling.
PCOS can disrupt a women’s fertility and other side effects like hair growth and acne. This disease can be detected early if you opt for regular preventive health checkups. To book an appointment for complete health checkup package fill in the inquiry form below.

Share The Gift Of Health - Best Valentine Gift 2019

Rather than gifting a bunch of roses, chocolates or over sized soft toys to your Valentine offer them some healthy and downright useful gifts this year. Think an extra mile to choose some lovely healthy Valentine’s gifts for your honey. There are endless thoughtful and healthy Valentine’s Day gift ideas to show you care.

Here’s what you should look forward to:

1. The Fit Bit
You must be overwhelmed with so many varieties of fitness trackers available on the market. Have you ever thought of gifting it to your partner on Valentine’s Day? The Fit Bit can be an ideal choice for this special occasion. The device is one of the best healthy Valentine’s Day gifts you can present to a fitness lover.

2. An Active Getaway
Does your sweetheart endeavor adventurous retreats? If yes, you can surprise your partner with an active gateway package. The thrill and excitement of an adventurous run or trek will give you an exhilarating vacation out from your daily schedule. You may also take cooking classes as healthy Valentine’s gifts for your spouse. These healthy memories will stay forever!

3. Essential Oils
You might have gifted a pack of yummy and healthy dark chocolate to your valentine before. This time try something different. Your health-conscious lover will admire a pack of essential oils. You may also indulge in a romantic oil massage to set up the mood. Orange, Lavender, Palmarosa, and Chamomile are some great choices to spark your mood.

4. Fitness Equipment
Gift your beloved a new set of weights, a tech-savvy smartwatch, resistance bands or a fancy sports jacket on Valentine’s Day. These are amazing healthy Valentine’s Day gifts that will brighten up your sweetheart’s day. You may pair these up with a greeting card or a rose, packed with lots of love!

5. Health Checkup Package
Are you still trying to figure out the finest healthy Valentine’s Day gifts for your partner? Have you bought a preventive health checkup package yet? No! Then head straight to your nearest health center and book a fitness checkup package to suit your needs.

It’s Valentine’s Day and you have to make sure your beloved is healthy and safe. Sweets and roses will perish soon, but a healthy valentine gift idea would be enjoyed for a lifetime. Get full body checkup packages for your loved ones now.

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